Journal article
When knowledge of a heritable gene mutation comes out of the blue: Treatment-focused genetic testing in women newly diagnosed with breast cancer
B Meiser, VF Quinn, M Gleeson, J Kirk, KM Tucker, B Rahman, C Saunders, KJ Watts, M Peate, E Geelhoed, K Barlow-Stewart, M Field, M Harris, YC Antill, G Mitchell
European Journal of Human Genetics | SPRINGERNATURE | Published : 2016
DOI: 10.1038/ejhg.2016.69
Abstract
Selection of women for treatment-focused genetic testing (TFGT) following a new diagnosis of breast cancer is changing. Increasingly a patient's age and tumour characteristics rather than only their family history are driving access to TFGT, but little is known about the impact of receiving carrier-positive results in individuals with no family history of cancer. This study assesses the role of knowledge of a family history of cancer on psychosocial adjustment to TFGT in both women with and without mutation carrier-positive results. In-depth semistructured interviews were conducted with 20 women who had undergone TFGT, and who had been purposively sampled to represent women both family histo..
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Funding Acknowledgements
We thank the patients who generously participated in this study. We also gratefully acknowledge the assistance of the surgeons and other staff who were involved at each site and who were integral to the success of this study. Thanks also to Mariana Souza for research assistance. We also acknowledge the support and endorsement of this project by the Psycho-oncology Cooperative Research Group (PoCoG).